Aging is a natural phenomenon and every human being fears for aging, getting old, and losing their physical fitness. Aging brings with it multiple diseases and disorders which makes aging even more dreadful. Although you can’t stop aging but you can slow it. In this era full of scientific innovation and technology experts have come up with several different ways of slowing the natural process of aging. One of the recently discovered processes is the "killing of zombie cells". Experts claim that killing zombie cells or senescent cells will slow down the aging process. But what are zombie cells?
In this blog post, we will tell you what zombie cells are, how you can get rid of senescent cells naturally, and what supplements you can use to eliminate zombie cells from your body. Along with this, we will also give an insight into the recent studies on zombie cells.
What are Zombie Cells?
What are zombie cells? Zombie cells are defined as the cells which have attained their maximum lifespan and are now reached at the age of cell death but they don’t die their natural death instead remain there in the body as living “dead” cells.
Zombie cells don’t perform the normal cell functions not even divide and multiply.
We all are aware of the fact that every cell of our body is meant to do specific functions. One of the important cellular functions is to divide and multiply which is a cell; natural life cycle and once this life cycle is completed the cells die a natural death and are replaced by the new healthy cells.
The natural phenomenon of cell death is called “Apoptosis” and biologists have claimed that a cell goes from the process of division and multiplication 40-60 times before apoptosis.
Natural cell death is important and beneficial to the human body since it gives birth to new healthy cells to replace the old worn-out cells. It also prevents the body from cancer. But some cells in our body don’t follow this regime of natural cell death instead they converted themselves into zombie cells and remain instead of the body as living dead cells.
How Zombie Cells are Produced?
During the process of aging human body goes from the process of cellular damage because of multiple factors, this cell damage results in the accumulation of damaged cells in the body. The DNA of these damaged cells doesn’t divide further as they enter the phase of cell senescence and are thus regarded as “aged cells”.
As time passes these aged and damaged cells start producing a toxin that affects the nearby healthy and active cells of the body and they too become a senescent cells.
Cell senescent is the main cause of aging and it further causes inflammation and the development of chronic diseases and other age-related diseases.
Firstly it was known that cell senescent is an important mechanism for the human body and it prevents the formation of tumors and replication of damaged cells in the body, thus it is considered as the defensive process for the human body. But with time as the research progresses, it was found that the senescent cell produces a special chemical that protects them from the natural process of cell death i.e. apoptosis. All these secretions are termed as Senescence-Associated Secretory Phenotypes (SASP) and they include:
- Destructive chemicals
- Immune Modulators
All these chemicals send signals to the immune system that these cells need to be removed from the human body.
With the aging process, several changes occur in the human body. One of the major changes in the disturbance of the mechanism that eliminates the aged cells from the human body. With the disturbance of this mechanism, these aged cells start accumulating in the human body and secrete their toxic chemicals.
These chemicals harm the normal healthy nearby cells and convert them into “zombie cells”. These zombie cells are linked with different harmful diseases like cancer, Alzheimer’s disease, osteoporosis, and other age-related physiological, metabolic, and psychological effects.
Factors Responsible for Cell Senescence
Several factors are involved in the process of cell senescence such as:
- Decreased Sirtuin level
- Damage to Telomeres
- Oxidative Stress
- DNA Damage
- Lack of Healthy Nutrients
- Metabolic Disorders
- Chronic Inflammation
- Damage to Mitochondria
Studies on Zombie Cells how they cause Harm to the Body
One of the important and cell is by researchers of Mayo clinic, they investigate that how senescent cells or you may call them zombie cells cause harm to the body through their contribution to diseases and illness.
A study in a mice model regarding the effect of zombie cells on bone loss concerning chemotherapy was conducted by Mayo Clinic in collaboration with Washington University School of Medicine and Mayo Clinic. The study suggests that zombie cells play an important role in the bone loss induced by chemotherapy irrespective of the estrogen levels of the mouse. The study was reported with the evidence that the depletion of the zombie cell in mice intact the bone density during chemotherapy.
Zombie cells trigger both good and bad responses in the body. The signals sent by zombie cells trigger the immune system to throw the damaged cells out of the body. On the other hand, these signals from toxic chemicals also cause chronic inflammation in the body. Because of this scientists started working on the mechanism in which the body can respond to the good signals while ditching the bad ones.
It has also been observed by scientists that obesity increases the production of zombie cells. It also affects the function of fat tissues throughout the body. Thus, obesity is a trigger for the production of zombie cells. Also, the mechanisms that occur because of obesity like senescence-associated secretory phenotype, zombie cells production, and others cause the severity of the obesity.
How to get rid of Zombie Cells Naturally
The first and foremost important way of getting rid of zombie cells is through the activity of the human immune system. For this purpose, you need to strengthen your immune system so that the process of cell senescence slows down and so the production of zombie cells. You can use substances that strengthen your immune system. During the process of aging, the human immune system becomes weak, thus zombie cells take the lead and start accumulating in different body organs and systems which causes inflammation and chronic diseases.
There is a vicious cycle that runs between the weak immune system. Zombie cells weaken the immune system and vice versa a weak immune system causes an increased production of zombie cells.
But in today’s age of modern science and technology, it is not a matter to worry about. Now scientists have come across many ways to tackle the production of zombie cells and slow the process of aging.
There are some natural products known as senolytics which are proved beneficial for the killing of zombie cells. The degree of effectiveness of these naturally occurring substances varies from one another. These substances include:
- Curcumin Analog
More extensive research in this field to find out more substances and their potential against zombie cells are on the way.
What is Quercetin?
Quercetin is a natural pigment and a plant flavonoid that has special properties like anti-inflammatory and anti-oxidant properties to fight against different diseases like:
- Heart Diseases
Quercetin is naturally found in the following foods:
- Red Wine
- Buckwheat Tea
- St John’s wort
- Green Tea
- Gingko Biloba
Another important function of Quercetin is its activity of boosting up the level of NAD+ in the body that regulates the production of sirtuins, a special protein that regulates the process of cell death.
What is Fisetin?
Fisetin is a naturally occurring polyphenol and flavonoid which have high health benefits along with anti-oxidant and anti-inflammatory properties. They target different diseases including:
- Cardiac Diseases
- Neurodegenerative Diseases
Fisetin is naturally present in almost all everyday use foods, the most important food sources of Fisetin are:
Fisetin has great potential against aging and other cellular damage processes and increasing overall lifespan.
Both the above-mentioned substances i.e. Quercetin and Fisetin have a great potential in getting rid of zombie cells naturally and slowing down the natural process of aging.
Killing of Zombie Cells through Supplements
Now different supplements are also available in the market to kill the Senescent Cells that increase the lifespan. One of the pharmaceutical products is Metformin, which is given to diabetic patients. Now this drug has gained popularity for its effectiveness against anti-aging and age-related diseases. It slows down the process of cell senescence.
With the use of naturally occurring as well as supplements, you can now get rid of zombie cells and slow your process of aging and age-related problems.