The Foxo Genes family, particularly FOXO3, has garnered significant attention in scientific circles due to its fundamental role in aging and combating age-related diseases. Forkhead box O3, or FOXO3, is a protein that acts as a cellular control center, managing critical functions like cell growth, DNA repair, and the removal
Interest in the mTOR Longevity Pathway is rising among health-focused individuals. mTOR stands for “mechanistic target of rapamycin.” It’s a protein that controls cell growth and energy use. It serves as an internal sensor, guiding cells to expand with plenty of nutrients or save resources when scarce. mTOR’s responsive nature
Have you ever thought about how our bodies manage energy and metabolism? At the heart of these mechanisms is an enzyme known as Adenosine monophosphate-activated protein kinase, or simply AMPK. It acts like an energy detector and has a big impact on how our bodies handle energy. When exploring AMPK
Humans have long searched for ways to prolong their lives. From the epic tales of ancient Greece to the latest blockbusters and page-turners, the yearning for immortality has been a persistent theme throughout history. However, unlike the fantastical stories of the old, the secret to a long life is not
table of contents How do you stay fit and active? Maybe you go for walks, lift weights, or follow a structured program. Movement comes in many forms — and the good news is that almost all of it supports your health. Still, research shows that some types and amounts of
table of contents A longevity-focused diet plays a significant role in how we age. From protecting against chronic disease to supporting cellular repair and metabolic balance, the food choices we make daily can directly impact both lifespan and healthspan. This guide explores how nutrition for longevity and diet and longevity
A review article, published in the journal Heliyon, provides a comprehensive overview of the current state of knowledge on liposomal delivery and the clinical applications of liposomes in the field of medicine. Liposomes are tiny spherical structures made up of a lipid bilayer that can be used to deliver drugs and
Introduction Several lifestyle and health-related exposures including alcohol intake, smoking, diet, physical activity and education are strongly linked with age-related health effects. Some common age-related health issues include heart disease and cancer. In addition, some lifestyle exposures also lead to modification of epigenetics, which ultimately affect gene expression related to
If you have been delving into longevity supplements like NAD+ and NMN lately, you must have heard about sirtuins. Sirtuins are a family of seven signalling proteins involved in several metabolic processes. While these proteins are found in the nucleus, cytoplasm, and mitochondria of human cells, mitochondrial sirtuins have especially
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Prof. Dr. Andrea Maier is an internist and professor of aging (“ longevity medicine ”) at the Vrije Universiteit in Amsterdam and the University of Melbourne, Australia. She studies the aging body and searches for anti-aging treatments. She heads the Center for Healthy Longevity in Singapore.
Why do we gradually decline during our average life of more than 80 years? Can we stop that process? Or maybe even turn around? And to what extent should we really want that? Maier gives practical tips on how we can extend our lifespan while also staying healthy.
Andrea Maier graduated in Medicine from the University of Lübeck in 2003. She specialized in internal medicine at the Leiden University Medical Center and subsequently chose the subspecialty of Geriatric Medicine. This is where she started her research into aging.
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