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Healthy Aging 101

Foxo protein genes explained, a possible road to increased longevity and better understanding of aging.

Understanding Foxo Genes: Key to Aging and Longevity

The Foxo Genes family, particularly FOXO3, has garnered significant attention in scientific circles due to its fundamental role in aging and combating age-related diseases. Forkhead box O3, or FOXO3, is a protein that acts as a cellular control center, managing critical functions like cell growth, DNA repair, and the removal

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View of the serene Rapa Nui landscape, the origin of rapamycin, against a backdrop of the ancient Moai statues symbolizing the mTOR pathway's link to longevity research and the quest to understand mTOR's role in aging.

The mTOR Longevity Pathway Explained | What is it?

Interest in the mTOR Longevity Pathway is rising among health-focused individuals. mTOR stands for “mechanistic target of rapamycin.” It’s a protein that controls cell growth and energy use. It serves as an internal sensor, guiding cells to expand with plenty of nutrients or save resources when scarce. mTOR’s responsive nature

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A sign showing long life, which is one of the pathways that AMPK could do: What is AMPK, highlighting the process of AMPK activation by AMPK metabolic activators for cellular energy balance.

What is AMPK and How Can Activator Supplements Enhance It?

Have you ever thought about how our bodies manage energy and metabolism? At the heart of these mechanisms is an enzyme known as Adenosine monophosphate-activated protein kinase, or simply AMPK. It acts like an energy detector and has a big impact on how our bodies handle energy. When exploring AMPK

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caloric restriction and longevity, a science-backed guide and strategy

Caloric Restriction and Longevity: a Science-Backed Strategy

Humans have long searched for ways to prolong their lives. From the epic tales of ancient Greece to the latest blockbusters and page-turners, the yearning for immortality has been a persistent theme throughout history. However, unlike the fantastical stories of the old, the secret to a long life is not

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Man is playng tennins, tennis ball in the air ready to serve. High sun exposure. Bird's-eye view

Exercises for longevity

table of contents How do you stay fit and active? Maybe you go for walks, lift weights, or follow a structured program. Movement comes in many forms — and the good news is that almost all of it supports your health. Still, research shows that some types and amounts of

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How do lifestyle and health related exposures contribute to epigenetic aging?

Epigenetic Aging: How do Lifestyle and Health-Related Exposures Contribute to it

Introduction Several lifestyle and health-related exposures including alcohol intake, smoking, diet, physical activity and education are strongly linked with age-related health effects. Some common age-related health issues include heart disease and cancer. In addition, some lifestyle exposures also lead to modification of epigenetics, which ultimately affect gene expression related to

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What are sirtuins and why are they important for longevity

What are Sirtuins?

If you have been delving into longevity supplements like NAD+ and NMN lately, you must have heard about sirtuins. Sirtuins are a family of seven signalling proteins involved in several metabolic processes. While these proteins are found in the nucleus, cytoplasm, and mitochondria of human cells, mitochondrial sirtuins have especially

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Prof. Dr. Andrea Maier

Prof. Dr. Andrea Maier is an internist and professor of aging (“ longevity medicine ”) at the Vrije Universiteit in Amsterdam and the University of Melbourne, Australia. She studies the aging body and searches for anti-aging treatments. She heads the Center for Healthy Longevity in Singapore.
Why do we gradually decline during our average life of more than 80 years? Can we stop that process? Or maybe even turn around? And to what extent should we really want that? Maier gives practical tips on how we can extend our lifespan while also staying healthy.

Topics Andrea Maier talks about

  • Health
  • Aging and rejuvenation
  • Interventions to reverse aging
  • Gerontology
  • Innovation in medicine
  • Medicine


Background Andrea Maier

Andrea Maier graduated in Medicine from the University of Lübeck in 2003. She specialized in internal medicine at the Leiden University Medical Center and subsequently chose the subspecialty of Geriatric Medicine. This is where she started her research into aging.

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