When cells lose NAD⁺: A new study shows a surprising virus-like response

A recent study published in Aging Cell in 2025 offers detailed insight into what happens when cells lose their supply of NAD⁺, one of the body’s most essential molecules for energy and repair. The researchers found, among other things, that when cells lose NAD⁺, they don’t just slow down — they activate a defense mechanism […]

Niacin vs. Nicotinamide vs. Niacinamide – What are the Differences?

When exploring vitamin B3 supplements or skincare products, you may encounter niacin, nicotinamide, and niacinamide. While they are related, their functions and uses differ. In this article, we explain these differences to help you choose the right form of vitamin B3 based on your needs. What is Niacin? Niacin, also known as nicotinic acid, is […]

Nicotinamide Riboside Benefits and Side Effects

Nicotinamide may sound like something from a science book, but it’s actually one of the most common forms of niacin, or vitamin B3, that’s included in supplements. Like other vitamin B3 forms, your body transforms nicotinamide riboside into nicotinamide adenine dinucleotide (NAD+).

NAD vs NAC: What Are the Main Differences?

While it’s not possible to stop time, many factors can affect how people age. Diet, in particular, plays a huge role in promoting healthy aging. In fact, research suggests that some supplements can help maintain sharpness and vitality as you get older. However, with so many products on the market claiming to be effective, it […]

7 NAD+ Precursors: What they are, how they work, and which ones look most effective

table of contents If you care about energy, recovery, or healthy aging, you’ll meet NAD+ fast. Cells use it to turn food into ATP, repair DNA, and run stress-response enzymes. Levels slide with age, which is why raising NAD+ is getting so much attention. A 2025 Nature Aging review pulls together what we know from […]

Foods That Contain and Boost Nicotinamide-Adenine–Dinucleotide (NAD+)

Our body needs different vitamins, enzymes, or fuels for additional requirements. Protein and other needs help build muscles. Carbohydrates give energy in a different way, and water keeps you from getting dehydrated. Also, it helps in digestion, and vitamins like A, C, and D help boost the immune system. Let’s see what foods are rich […]

NMN vs NR – The NAD+ precursor comparison

Most readers arrive here with a simple question: Which should I try—NMN vs NR? Both feed the same salvage pathway that keeps cellular NAD⁺ topped up. NR converts to NMN inside cells, and NMN is then one step from NAD⁺. Human trials show that both raise blood NAD⁺, but the details differ by study design, […]

What is NAD+: A vital molecule for health and longevity

NAD+ occurs in virtually every cell in your body. The molecule is involved in energy production, mitochondria and various processes around cell maintenance. It is precisely that central role that makes NAD+ an important topic within longevity and healthy ageing.¹ But what exactly is NAD+? What is the difference with NADH, why does the NAD+ […]