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30 day Money-back guarantee*Clinical trials in healthy adults aged 40–65 (including one led by Andrea Maier) have demonstrated that daily NMN doses of 300–900 mg for 60 days significantly raise blood NAD⁺ levels and improve physical performance—participants increased six‑minute walk distance by 14–50% without any adverse effects . Safety data confirmed excellent tolerability and stable lab markers across all dose groups . * EFSA-sanctioned claims regarding NMN’s anti-aging benefits are still under review.
In human trials involving over 1,000 participants, resveratrol supplementation (typically between 150–500 mg/day for 4–12 weeks) has been shown to support cardiometabolic health—improving glucose and lipid metabolism, lowering LDL and total cholesterol, and enhancing insulin sensitivity . A 30-day study of 500 mg per day reported measurable increases in SIRT1 activity comparable to a 1,000 kcal calorie-restriction diet . Resveratrol is generally well tolerated at these doses, though research indicates that doses above 1 g/day may occasionally cause mild gastrointestinal discomfort. * EFSA has not yet approved any health claims related to resveratrol.
Trans-Resveratrol (Japanese Knotweed Extract), Nicotinamide Mononucleotide (NMN), Lecithin (Sunflower), Maltodextrin (Bulking Agent), HPMC (Vegan capsules)
Take 2 capsules (up to 4) capsules of NMN and 1 capsules of Resveratrol in the morning with breakfast or on an empty stomach with a glass of water.
We offer free shipping to most European countries and the UK on orders above €50,-. We offer free shipping to Switzerland on orders over €75.
Orders placed before 15:00 CET are shipped the same day. Depending on your location it usually takes 1-5 business days for your order to arrive. Orders place after this time or in the weekend will be shipped the next business day.
Purovitalis Vital Core Duo
NMN without Resveratrol
Generic Energy Supplement
Sirtuins are a key element to aging well and staying healthy. To get the most out of this natural process, it is beneficial to combine Resveratol with NMN – two compounds that work in tandem for maximum longevity benefits.
Think of your cells as a powerful train. NAD⁺ is the coal that fuels it, keeping your energy and repair systems running. NMN supplies that fuel—restocking your body’s NAD⁺ levels as they naturally decline with age. Resveratrol? It’s the skilled operator that activates your cell’s longevity engine. On their own, they help—but together, they supercharge the ride. More fuel, more power, smoother aging.
Become your own expert in longevity with insightful articles, expert advice, and comprehensive information.
Become your own expert in longevity with insightful articles, expert advice, and comprehensive information.
NMN replenishes NAD⁺, essential for cellular health, while Resveratrol activates sirtuin genes—key regulators of longevity and cellular repair. Together, they enhance each other’s benefits for stronger energy, DNA protection, and anti-aging effects.
Many customers report energy, focus, and metabolism improvements within 2–4 weeks. Individual responses vary, but ongoing use over 90 days can help maximize benefits.
Yes. In a 60-day double-blind clinical trial led by Andrea B. Maier et al., healthy adults taking 300–900 mg NMN daily experienced no safety concerns—no adverse effects, stable lab tests, and excellent tolerability. Resveratrol, at doses below 500–1000 mg/day, is generally well tolerated—higher doses may cause mild GI issues in some.
Both are hampered by low oral bioavailability—NMN due to its phosphate group and Resveratrol because it’s rapidly metabolized. Liposomal encapsulation shields them through digestion and improves cellular uptake, potentially doubling absorption into tissues.
For best results, consistency matters. A one-off dose won’t meaningfully sustain NAD⁺ levels or sirtuin activation. These pathways require ongoing support—hence a regimen like our bundle is much more effective in maintaining cellular health over time.
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Experts agree: real benefits from vitamins and longevity products come with regular, long-term use. That’s why we offer a 3-month minimum commitment, so you can give your body the time it needs to truly benefit.
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Prof. Dr. Andrea Maier is an internist and professor of aging (“ longevity medicine ”) at the Vrije Universiteit in Amsterdam and the University of Melbourne, Australia. She studies the aging body and searches for anti-aging treatments. She heads the Center for Healthy Longevity in Singapore.
Why do we gradually decline during our average life of more than 80 years? Can we stop that process? Or maybe even turn around? And to what extent should we really want that? Maier gives practical tips on how we can extend our lifespan while also staying healthy.
Andrea Maier graduated in Medicine from the University of Lübeck in 2003. She specialized in internal medicine at the Leiden University Medical Center and subsequently chose the subspecialty of Geriatric Medicine. This is where she started her research into aging.
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